BrainMD Brain & Memory Power Boost
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BrainMD Brain & Memory Power Boost falls short.
A doctor-formulated brain-and-memory stack from Dr. Daniel Amen's BrainMD line. Two of the four headline ingredients (PS, Huperzine A) meet our reference doses; ALCAR, at 665mg, is below the 1.5–3g/day used in its positive trials, and Ginkgo, at 120mg, is half the 240mg reference dose. Positioned for older adults and patients in the Amen Clinics ecosystem.
What it does
BrainMD Brain & Memory Power Boost is the flagship cognitive product from BrainMD, the supplement company founded by Dr. Daniel Amen — the psychiatrist and bestselling author known for the Amen Clinics and SPECT imaging-based brain assessments. The product is a 6-ingredient memory-and-aging-focused stack manufactured to pharmaceutical-grade quality standards in current Good Manufacturing Practice (cGMP) compliant facilities. It is sold direct via brainmd.com, on Amazon, and through Costco, with broad reach into the older-adult and clinician-referred consumer segment.
How it works
Phosphatidylserine supports neuronal membrane fluidity and carries an FDA-qualified health claim for cognitive decline. Acetyl-L-Carnitine crosses the blood-brain barrier, supports mitochondrial energy in neurons, and has trial evidence for mild cognitive impairment. Ginkgo Biloba improves cerebral blood flow via vasodilation and PAF inhibition. Huperzine A is a reversible acetylcholinesterase inhibitor that elevates synaptic acetylcholine — clinically used for memory in some markets. NAC (400mg) and Alpha Lipoic Acid (200mg) complete the formula; we have no reference dose on file for either.
What to expect
This is a long-game memory product — expect minimal day-one effects. Within 2-4 weeks: subtle improvements in word retrieval and short-term recall (Ginkgo + Huperzine A). At 8-12 weeks: cumulative membrane and mitochondrial benefits from PS and ALCAR. Best suited for adults over 50 working on long-term memory maintenance rather than acute focus. Huperzine A has a long half-life; no trial has tested a cycling schedule, so follow the label and stop if you notice cholinergic side effects (nausea, cramps, vivid dreams).
Hero ingredients
- Phosphatidylserine100mg
- Acetyl-L-Carnitine665mg
- Ginkgo Biloba120mg
- Huperzine A100mcg
Who it's for
- Two of four headline ingredients (PS, Huperzine A) at our reference doses
- Pharmaceutical-grade cGMP manufacturing
- Caffeine-free
Who should skip
- Acetyl-L-Carnitine (665mg) and Ginkgo (120mg) below our reference doses
- $64.95/month list price on brainmd.com (30 servings at 4 capsules per day)
- 4 capsules per serving
Dosing audit
| Ingredient | Label | Clinical | Status |
|---|---|---|---|
| Acetyl-L-Carnitine (as acetyl-L-carnitine HCl) | 665mg | 1500-3000mg/day | ✕ Under |
| N-Acetyl-L-Cysteine (NAC) | 400mg | No reference dose on file | ? Unverified |
| Alpha Lipoic Acid | 200mg | No reference dose on file | ? Unverified |
| Ginkgo Biloba Extract (leaf; 24% ginkgo flavonols, 6% terpene lactones) | 120mg | 240mg/day (24/6 extract) | ✕ Under |
| Phosphatidylserine (SharpPS Green, from sunflower) | 100mg | 100-300mg/day | ✓ Pass |
| Huperzine A (Huperzia serrata whole-herb extract) | 100mcg | 100-200mcg/day | ✓ Pass |
Ingredient quality
Number and quality of evidence-graded ingredients. Trademarked extracts and standardized actives raise this score.
Dosing vs. clinical evidence
The share of ingredients with a reference dose on our ingredient pages whose label-stated daily amount meets that page's minimum. Amounts the label hides (blend shares) or states on a different basis count as not met; ingredients with no reference page are listed but not scored.
Formula transparency
Full disclosure of every ingredient at its exact dose. Proprietary blends are scored as opaque.
Value for money
Cost per month relative to per-serving clinical doses delivered. Cheaper products with underdoses score lower.
Brand trust
Brand reputation, third-party testing, refund track record, and Trustpilot signal across multiple years.
How the score is computed
Each pillar is weighted by editorial importance. Weights are constant across every brand we audit — they're not adjusted to favour any particular product.
- Ingredient quality25%
- Dosing vs. clinical evidence30%
- Formula transparency20%
- Value for money15%
- Brand trust10%
No Trustpilot profile
BrainMD (Dr. Daniel Amen) doesn't have an active Trustpilot listing — this is common for Amazon-only sellers, marketplace brands, and regional pharmacy chains.
The Trust pillar in our editorial score still applies and reflects brand reputation, third-party testing, and refund track record.
What the vendor’s site says
Quoted word for word from the vendor’s own pages. Terms change, so check them before you buy.
Shipping
Free Economy shipping is available on orders over $75 (Excludes Alaska, Hawaii, American Samoa, Guam, U.S. Virgin Islands, Northern Mariana Islands, and Puerto Rico).
Per brainmd.com (opens in new tab), checked
Cancelling a subscription
Online cancellation is currently limited to California residents. All other customers can cancel by reaching out to our Customer Care Team via email, phone, or live chat (see below).
Per brainmd.com (opens in new tab), checked
One-time purchase price
One-time purchase 1 Unit one-time delivery $64.95
Per brainmd.com (opens in new tab), checked
Returns
Return unopened products within 60 days of purchase for a full refund of the purchase price (less original and return shipping costs).
Per brainmd.com (opens in new tab), checked
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We earn a commission if you buy through links on this page, at no extra cost to you. Our scores and rankings follow our published methodology; commissions do not influence them.
Buying in the United States
- Local price
- $64.95/month
Ingredient amounts from BrainMD's label at https://cdn.shopify.com/s/files/1/0696/2656/0681/files/Brain-And-Memory-Power-Boost-Supplement-BrainMD-6.png?v=1767895544, checked 2026-10-08.
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Health disclaimer
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Information on this page is for educational purposes only and is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you are pregnant, nursing, taking medication, or have a medical condition. Individual results vary.